iFOUR – Benchtop Microdispensing for pL - µL
Reproducible dispensing for miniaturized, high-throughput workflows.
The iFOUR enables precise, non-contact liquid handling for developing and prototyping diagnostic microarrays, biosensors and lab-on-a-chip applications.
Configure your iFOUR Talk to an expert
Key Benefits:
- Volume Range: Reliable dispensing from 10 pL up to 1 µL.
- Application Ready: Optimized for microarray printing, biosensor coating, and Lab-on-a-Chip.
- Minimal Footprint: Compact, benchtop design for easy lab integration.
- Zero-Contact: Protect sensitive reagents with Valve or Piezo-driven technology.
The iFOUR
The iFOUR microdispensing instrument provides precise, non-contact liquid handling from picoliters to microliters in a compact benchtop format. It integrates seamlessly into existing lab setups and complements conventional pipetting and liquid handling workflows.
Dispensing Technology
Our non-contact microdispensing technology covers volumes from microliters down to picoliters and is designed for flexible, high-precision liquid handling. It is ideal for limited and sensitive samples in applications such as microarray printing and assay miniaturization.
Applications
The iFOUR is a reliable tool for advanced microdispensing applications in diagnostics and life science: from developing tests and loading biosensors with proteins, aptamers or oligonucleotides to creating microarrays on chips, slides and microtiter plates.
Precision in every drop: Tailored solutions for your application
Whether you are developing diagnostic microarrays, biosensors, lab-on-a-chip devices or cell-based assays, the iFOUR supports a broad range of substrates and sample types, ensuring a seamless transition from R&D to production.
High-Density Microarray Printing
Achieve high-density microarray printing with excellent spot-to-spot consistency on slides, membranes or custom substrates. Non-contact picoliter dispensing keeps proteins, DNA and antibodies highly active with low CVs.
Advanced Biosensor Functionalization
Precisely functionalize biosensors by coating electrodes and optical sensing areas with aptamers, antibodies or enzymes. Camera-guided alignment ensures accurate placement even on very small sensing spots.
Lab-on-a-Chip & Microfluidic Loading
Load lab-on-a-chip and microfluidic devices with pL-µL accuracy into micro-channels, reaction wells and complex chip geometries. The compact benchtop iFOUR supports fast prototyping and small-scale production.
Seamless Assay Miniaturization
Move from conventional pipetting to high-precision pico- to microliter dispensing for multiplex diagnostics and drug screening assays. The iFOUR reduces sample consumption and accelerates validation of miniaturized workflows.
Configure your iFOUR
Your microdispensing instrument is just a few steps away: Request your non-binding offer today using the online configurator.
News & Updates
See the iFOUR in Boston at SLAS 2026
09 - 11 February 2026 | Boston, MA, United States
SLAS 2026 is back in Boston, and lab automation takes center stage. Our distribution partner axiVEND will present the iFOUR microdispenser at the 2026 SLAS International Conference and Exhibition at booth 1727. They will demonstrate how the iFOUR enables fast dispensing of extremely small volumes, making it ideal for precise, highly reproducible assay setups as well as busy screening and automation workflows.
Discover picoliter precision at analytica 2026
24 - 27 March 2026 | Messe München, Germany
Why settle for less than world-class microdispensing when you can have it without compromising bench space? Visit analytica 2026 to see the iFOUR in action at the M2-Automation booth 338 in Hall B1. The iFOUR provides compact, non-contact dispensing from pL to µL, ensuring reproducible results. It pairs perfectly with the high-throughput iONE system, which will also be showcased.
Ready to scale up
The iFOUR benchtop microdispenser delivers high-precision single channel dispensing for research and development. When you need higher throughput, our sister company M2-Automation provides fully customized multi channel systems built for scalable production workflows.
Ideal for multiplexed diagnostics, biosensor functionalization, microfluidic chip loading, and high throughput assay development.
Spot detection with integrated head camera
Use the iFOUR integrated head camera for reliable spot detection and quality control. Define target positions and reference points on your substrate, then identify spots manually or capture them automatically during the run. This video walks you through the setup and workflow step by step.
High-capacity Piezo Microdispensing
Introducing the PDMD-L, a high-capacity Piezo-Driven Microdispenser designed to cover a broader volume range with a single dispenser. Reduce changeovers, simplify setup, and streamline your microdispensing workflow. Watch the video and discover more on the YouTube channel.
Droplet Optimization with InDot Software
Discover the power of droplet optimization with the iFOUR wash station's built-in droplet camera. Watch as we guide you through the process of setting up your dispenser for precise pico liter dispensing with a Piezo-Driven Microdispenser (PDMD).
Lab Automation and Ressource Management
How can automated microdispensing enhance laboratory sustainability? In a featured article for LABO magazine, experts from M2-Instruments and M2-Automation share insights into eco-friendly lab automation.
Trusted by leading diagnostics and life science innovators
A selection of diagnostics, biosensor and life science companies that use microdispensing systems from M2-Instruments.
M2-Instruments Info Service
Get the latest info.
Subscribe to our info service and we will keep you up to date on any news about the iFOUR.